Microscopy

Fluorescence Imaging Design System

01 — Color Palette

Fluorescent Channels

Colors drawn from fluorescence microscopy stains. Each channel corresponds to a specific fluorophore excitation/emission spectrum, rendered on a darkfield background.

Darkfield Substrates

Substrate
#030308
Slide Dark
#060610
Well Plate
#0a0a18
Coverslip
#0e0e20
Mounting Medium
#12122a
Stage
#181833

GFP / FITC Channel (Green)

GFP Bright
#00ff66
GFP Core
#00e05a
GFP Mid
#00b848
GFP Dim
#008a36
GFP Faint
#005c24

Rhodamine / Texas Red Channel (Magenta)

Rhodamine Bright
#ff00cc
Rhodamine Core
#dd00b0
Rhodamine Mid
#b80090
Rhodamine Dim
#880068
Rhodamine Faint
#580044

DAPI / Hoechst Channel (Cyan)

DAPI Bright
#00ccff
DAPI Core
#00aadd
DAPI Mid
#0088bb
DAPI Dim
#006699
DAPI Faint
#004466

Electron Microscope Grayscale

EM White
#d8d8e0
EM Light
#a0a0b0
EM Mid
#707080
EM Dark
#404050
EM Shadow
#28283a
02 — Typography

Specimen Labels & Data

Clean, scientific typefaces. Instrument Sans for display headings, IBM Plex Sans for body text, and IBM Plex Mono for data readouts, scale bars, and specimen labels.

Display / Instrument Sans 700
Cellular Imaging
FamilyInstrument Sans
Weight700 Bold
Size3.2rem / 51.2px
Heading XL / Instrument Sans 700
Fluorescent Protein Expression
FamilyInstrument Sans
Weight700 Bold
Size2.2rem / 35.2px
Heading / Instrument Sans 600
Confocal Z-Stack Acquisition
FamilyInstrument Sans
Weight600 SemiBold
Size1.6rem / 25.6px
Subheading / Instrument Sans 500
Mitochondrial membrane potential measured via TMRE staining
FamilyInstrument Sans
Weight500 Medium
Size1.2rem / 19.2px
Body / IBM Plex Sans 400
Fluorescence microscopy enables visualization of specific proteins, organelles, and cellular structures through targeted fluorescent labeling. By exciting fluorophores at specific wavelengths, researchers can observe subcellular localization patterns and dynamic processes in living cells.
FamilyIBM Plex Sans
Weight400 Regular
Size1rem / 16px
Caption / IBM Plex Mono 400
Fig. 3A — HeLa cells transfected with GFP-tubulin, counterstained with DAPI. Scale bar = 20 μm. Objective: 63x/1.4 Oil DIC.
FamilyIBM Plex Mono
Weight400 Regular
Size0.75rem / 12px
Monospace Data / IBM Plex Mono 500
EX/EM: 488/509 nm · Gain: 850V · Pinhole: 1 AU · Pixel dwell: 2.05 μs
FamilyIBM Plex Mono
Weight500 Medium
Size0.85rem / 13.6px
03 — Spacing

Spatial Scale

A 4px base unit spacing system. Consistent intervals maintain the precision expected of scientific instrumentation interfaces.

xs — 4px
sm — 8px
md — 16px
lg — 32px
xl — 64px
2xl — 96px
50 μm
04 — Buttons

Controls & Actions

Instrument panel controls. Primary actions use fluorescent GFP green for visibility against dark backgrounds. Secondary and destructive actions use DAPI and Rhodamine channels.

Primary Actions

Secondary & Variant Actions

Disabled States

05 — Forms

Acquisition Parameters

Input fields for configuring imaging parameters. Clean borders with fluorescent focus states emulate instrument control panels.

Unique identifier for this sample
06 — Cards

Specimen Gallery

Image cards with simulated fluorescence micrographs. Each card represents a captured field of view with metadata and channel information.

20 μm

GFP-Tubulin Expression

Microtubule network visualized via GFP-tagged alpha-tubulin in fixed HeLa cells. 488 nm excitation, 509 nm emission.

50 μm

Nuclear Morphology

DAPI-stained nuclei showing chromatin condensation patterns during mitotic phases. 405 nm excitation, 461 nm emission.

10 μm

Multi-Channel Merge

Three-channel composite: GFP-actin (green), MitoTracker Red (magenta), DAPI nuclei (cyan). Confocal z-projection.

07 — Alerts

System Notifications

Status messages for imaging workflows. Color-coded by fluorescent channel to indicate severity and context.

Acquisition in Progress
Z-stack capture running. Slice 14 of 28 complete. Estimated time remaining: 3m 42s.
Image Saved Successfully
HeLa-GFP-001_z14.tiff written to /data/experiments/2024-03-15/. File size: 48.2 MB.
Signal Saturation Detected
Channel 488 nm showing pixel saturation in ROI. Consider reducing laser power or exposure time.
Laser Interlock Triggered
Safety interlock activated on 561 nm laser line. Check enclosure door and reset before continuing.
08 — Well Plate

Multi-Well Layout

Grid-based specimen visualization inspired by microplate readers and high-content screening. Each well represents a different experimental condition or staining protocol.

Plate ID: EXP-2024-0315-A
09 — Channel Selector

Filter Cube Controls

Toggle fluorescence channels on and off to view individual stains or composite overlays. Modeled after microscope software filter panels.

10 — Specimen Viewer

Image Viewport

A simulated microscope viewport with CSS-rendered fluorescent cell structures. Demonstrates how cards and panels compose around an imaging workspace.

40x · GFP + DAPI · Z: 7/14
25 μm
11 — Navigation

Tab & Menu Bars

Navigation components styled as instrument software panels. Monospaced labels with subtle fluorescent active states.

12 — Data Table

Acquisition Log

Tabular data presentation for experiment records and measurement results. Channel indicators provide at-a-glance fluorophore identification.

Image ID Channel Exposure Laser % Mean Intensity Status
IMG-0042 GFP 488 200 ms 15% 2,847 Complete
IMG-0043 DAPI 405 100 ms 8% 4,102 Complete
IMG-0044 Rhodamine 561 350 ms 22% 1,563 Saturated
IMG-0045 YFP 514 250 ms 12% 3,291 Complete
IMG-0046 GFP 488 200 ms 15% Failed
13 — Design Principles

Imaging Philosophy

Core principles guiding this design system, drawn from the rigor and precision of scientific microscopy.

01
Darkfield First

Like fluorescence microscopy itself, content emerges from darkness. The near-black substrate ensures fluorescent accents achieve maximum contrast and visual impact.

02
Channel Specificity

Each color serves a distinct semantic purpose, just as each fluorophore binds to a specific target. Green for primary actions, cyan for information, magenta for warnings and destructive operations.

03
Quantitative Precision

Typography and spacing follow exact scales. Monospaced readouts present data without ambiguity. Every measurement has units, every specimen has a label.

04
Signal Over Noise

Minimize visual noise. Borders are subtle, backgrounds are restrained, and glow effects are used sparingly to draw attention only where it matters most.